Recombinant Pig Interferon gamma protein (ab92801)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Yeast
  • アミノ酸配列
    • 生物種
      Pig
    • 配列
      QAPFFKEITI LKDYFNASTS DVPNGGPLFL EILKNWKEES DKKIIQSQIV SFYFKFFEIF KDNQAIQRSM DVIKQDMFQR FLNGSSGKLN DFEKLIKIPV DNLQIQRKAI SELIKVMNDL SPRSNLRKRK RSQTMFQGQR ASK

特性

Our Abpromise guarantee covers the use of ab92801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Trehalose, 1X PBS

  • 再構成
    Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

関連情報

  • 別名
    • IFG
    • IFI
    • IFN gamma
    • IFN, immune
    • IFN-gamma
    • IFNG
    • IFNG_HUMAN
    • Immune interferon
    • Interferon gamma
    see all
  • 機能
    Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  • 組織特異性
    Released primarily from activated T lymphocytes.
  • 関連疾患
    In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
  • 配列類似性
    Belongs to the type II (or gamma) interferon family.
  • 翻訳後修飾
    Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab92801 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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