製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli

関連製品

特性

Our Abpromise guarantee covers the use of ab9796 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性

    Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 製品の状態Lyophilised
  • 備考The ED50 was determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED50 is < 1.0 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Please reconstitute this product in 200ul sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.

関連情報

  • 別名
    • Beta nerve growth factor
    • Beta NGF
    • Beta-nerve growth factor
    • Beta-NGF
    • HSAN5
    • MGC161426
    • MGC161428
    • Nerve growth factor
    • Nerve growth factor (beta polypeptide)
    • Nerve growth factor beta
    • Nerve growth factor beta polypeptide
    • Nerve growth factor beta subunit
    • NGF
    • NGF_HUMAN
    • NGFB
    • NID67
    see all
  • 機能Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
  • 関連疾患Neuropathy, hereditary sensory and autonomic, 5
  • 配列類似性Belongs to the NGF-beta family.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant NGF protein (ab9796) 使用論文

ab9796 has not yet been referenced specifically in any publications.

Product Wall

Ab9796 is a noncovalently disulfide-linked homodimer, of two 13.5kDa polypeptide monomers (238 total amino acid residues). The three disulfide bonds are required for biological activity.

As you have probably seen from the online datasheet, ab9796 -- NGF beta (human) recombinant protein -- is not currently in stock. The lead time for this item would be approx 7 working days. If you were to order 6 units on a single purchase order I coul...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"