製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli

特性

Our Abpromise guarantee covers the use of ab9840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Functional Studies

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 製品の状態Lyophilised
  • 備考Human Neurturin is fully biologically active when compared to standards. Human Neurturin at a concentration of 100ng/ml will support the survival of 65% of newborn rat sympathetic neurons.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

  • 再構成Reconstitute in water to a concentration of 0.1mg/ml

関連情報

  • 別名
    • Neurturin
    • Neurturin precursor
    • NRTN
    • NRTN_HUMAN
    • NTN
    • prepro-neurturin
    see all
  • 機能Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
  • 関連疾患Defects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
  • 配列類似性Belongs to the TGF-beta family. GDNF subfamily.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant Neurturin protein (ab9840) 使用論文

ab9840 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"