製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected Sf9 cells
  • アミノ酸配列
    • アクセッション番号P58750
    • 生物種Mouse
    • 分子量63 kDa including tags
    • 領域1 to 326

関連製品

特性

Our Abpromise guarantee covers the use of ab125561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性The specific activity of ab125561 is 785 nmol/min/mg.
  • アプリケーション

    Western blot

    Functional Studies

    SDS-PAGE

  • 精製度> 90 % Densitometry.
    ab125561 is >90% pure.
  • 製品の状態Liquid
  • 備考

    ab204879 (RPS6 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • Kid 1
    • Kid1
    • Kinase induced by depolarization
    • ONCOGENE PIM3
    • PIM 3
    • Pim 3 oncogene
    • Pim-3 proto-oncogene, serine/threonine kinase
    • PIM3
    • Pim3 oncogene
    • PIM3_HUMAN
    • Protein kinase Kid 1
    • Protein kinase Kid1
    • Serine/threonine kinase Pim 3
    • Serine/threonine kinase Pim3
    • Serine/threonine protein kinase Pim 3
    • Serine/threonine protein kinase Pim3
    • Serine/threonine-protein kinase Pim-3
    see all
  • 機能Able to phosphorylate CDKN1B in vitro. Involved in cell cycle progression and suppression of apoptosis. Implicated in proliferation of human hepatoma cell lines.
  • 組織特異性Widely expressed. No expression in colon, thymus, and small intestine. Expressed in human hepatoma cell lines but not in normal liver tissues. Expressed in colon cancer samples, particularly at the less advanced stages of cancer development.
  • 配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt

Recombinant mouse PIM3 protein 画像

  • The specific activity of ab125561 was determined to be 785 nmol/min/mg.
  • SDS PAGE analysis of ab125561 (PIM3 protein).

Recombinant mouse PIM3 protein (ab125561) 使用論文

ab125561 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"