Recombinant Mouse PSPN protein (ab56287)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
製品の詳細
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製品名
Recombinant Mouse PSPN protein
PSPN タンパク質・ペプチド 製品一覧 -
生理活性
The ED50 was determined by its ability to stimulate proliferation of human thyroid carcinoma cells (TT cells) is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
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精製度
> 95 % SDS-PAGE.
Greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg). -
発現系
Escherichia coli -
タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Mouse -
配列
ALAGSCRLWS LTLPVAELGL GYASEEKVIF RYCAGSCPQE ARTQHSLVLA RLRGRGRAHG RPCCQPTSYA DVTFLDDQHH WQQLPQLSAA ACGCGG -
領域
61 to 156
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特性
Our Abpromise guarantee covers the use of ab56287 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Functional Studies
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Upon delivery aliquot. Upon reconsitution add a carrier protein (0.1% BSA). Store at -20°C. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C..
Constituent: 0.294% Sodium citrate
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Reconstitute in water to a concentration of 0.1-1.0 mg/ml
関連情報
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別名
- Persephin
- PSP
- PSPN
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関連性
PSPN is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. PSPN has a similar structure to other family members, glial cell line-derived neurotrophic factor, Artemin and neurturin. All these proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. PSPN signals through a multicomponent receptor system, composed of RET and one of four GFR alpha (alpha1-alpha4) receptors. The GFRalpha4 was first identified in chicken and was later shown to be the preferential binding subunit for PSPN. In contrast to GDNF and Neurturin, PSPN does not support survival of peripheral neurons. -
細胞内局在
Secreted
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab56287 は論文での使用が確認できていません。