製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected Sf9 cells
  • アミノ酸配列
    • 生物種Mouse

特性

Our Abpromise guarantee covers the use of ab61414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Specific activity: 259 nmol/min/mg.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 製品の状態Liquid
  • 備考

    ab43614 (Human Myelin Basic Protein full length protein) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • Beta PAK
    • bPAK
    • CDKN1A
    • hPAK3
    • Mental retardation X linked 30
    • MRX30
    • MRX47
    • Oligophrenin 3
    • OPHN3
    • p21 (CDKN1A) activated kinase 3
    • p21 activated kinase 3
    • p21 CDKN1A activated kinase 3
    • P21 protein (Cdc42/Rac) activated kinase 3
    • PAK-3
    • PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
    • PAK3beta
    • Pak65alpha
    • Pak65beta
    • Serine threonine protein kinase PAK 3
    • Stk4
    see all
  • 関連性PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. PAK3 forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. It may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. A point mutation in this gene has been linked to nonsyndromic X-linked mental retardation.
  • 細胞内局在Cytoplasmic

Recombinant mouse PAK3 protein 画像

Recombinant mouse PAK3 protein (ab61414) 使用論文

ab61414 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab61414.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"