Recombinant mouse Interferon gamma protein (ab9922)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Mouse
    • 配列Recombinant Murine IFN-g is a 15.6 kDa protein containing 134 amino acid residues: MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLR LFEVLKDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV N NPQVQRQAF NELIRVVHQLLPESSLRKRK RSRC

関連製品

特性

Our Abpromise guarantee covers the use of ab9922 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 製品の状態Lyophilised
  • 備考The ED50 is <0.2ng/ml, determined by ability to inhibit proliferation of murine WEHI-279 cells, corresponding to a specific activity of >5 x 106 units/mg
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Please reconstitute this product in 5-10mM Sodium Phosphate, pH 8.0 to a concentration of 1.0mg/ml.

関連情報

  • 別名
    • IFG
    • IFI
    • IFN gamma
    • IFN, immune
    • IFN-gamma
    • IFNG
    • IFNG_HUMAN
    • Immune interferon
    • Interferon gamma
    see all
  • 機能Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  • 組織特異性Released primarily from activated T lymphocytes.
  • 関連疾患In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
  • 配列類似性Belongs to the type II (or gamma) interferon family.
  • 翻訳後修飾Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant mouse Interferon gamma protein (ab9922) 使用論文

ab9922 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Application Functional Studies
We used the recombinant IFN-g protein in cell culture. It reconstituted easily, and worked well in vitro to stimulate cells.
Username

Ms. Cheryl Sandoval

Verified customer

投稿 Sep 13 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"