Recombinant mouse iNOS protein (ab58951)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Mouse

特性

Our Abpromise guarantee covers the use of ab58951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    Specific Activity >7 units/mg protein.
  • アプリケーション

    Functional Studies

  • 製品の状態
    Liquid
  • 備考
    The enzyme loses approximately 10% of its activity after a single freeze-thaw cycle. During use, keep the solution on ice at all times.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 1.19% HEPES, 10% Glycerol, 0.001% Tetrahydrobiopterin

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • HEP-NOS
    • Hepatocyte NOS
    • HEPNOS
    • inducible
    • Inducible nitric oxide synthase
    • Inducible NO synthase
    • Inducible NOS
    • iNOS
    • MAC NOS
    • Macrophage NOS
    • Nitric oxide synthase
    • Nitric oxide synthase 2 inducible
    • Nitric oxide synthase 2 inducible macrophage
    • nitric oxide synthase 2A (inducible, hepatocytes)
    • Nitric oxide synthase inducible
    • nitric oxide synthase, macrophage
    • NOS
    • NOS 2
    • Nos II
    • NOS type II
    • nos2
    • NOS2_HUMAN
    • NOS2A
    • NOS2A, Inducible, Hepatocyte
    • Peptidyl-cysteine S-nitrosylase NOS2
    see all
  • 機能
    Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
  • 組織特異性
    Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
  • 配列類似性
    Belongs to the NOS family.
    Contains 1 FAD-binding FR-type domain.
    Contains 1 flavodoxin-like domain.
  • Information by UniProt

参考文献

ab58951 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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