製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Mouse
    • 分子量
      17 kDa
    • 領域
      21 to 169

特性

Our Abpromise guarantee covers the use of ab119728 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    The ED50 range is 0.1-0.4 ng/ml, as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells.
  • アプリケーション

    SDS-PAGE

    HPLC

    Functional Studies

  • 精製度
    > 98 % SDS-PAGE.
    Purity: >98% by SDS-PAGE and HPLC analysis. Endotoxin level is <0.1 ng per µg of IL2.
  • 製品の状態
    Lyophilised
  • 備考
    ab119728 is best-stored desiccated.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).

    pH: 4.00
    Constituent: 0.26% Sodium citrate

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    Centrifuge the vial prior to opening. Reconstitute in 100 mM AcOH to a concentration of 0.1-1 µg/µl to regain full activity. The solution can then be diluted into other aqueous buffers.

関連情報

  • 別名
    • Aldesleukin
    • IL 2
    • IL-2
    • IL2
    • IL2_HUMAN
    • Interleukin 2
    • Interleukin-2
    • Involved in regulation of T cell clonal expansion
    • Lymphokine
    • OTTHUMP00000164090
    • POIL2
    • T Cell Growth Factor
    • T-cell growth factor
    • TCGF
    see all
  • 機能
    Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
  • 関連疾患
    Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
  • 配列類似性
    Belongs to the IL-2 family.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab119728 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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