Recombinant mouse Hsp70 protein (ab113187)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q61696
    • 生物種Mouse
    • 分子量70 kDa
    • 領域1 to 641

特性

Our Abpromise guarantee covers the use of ab113187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性ATPase activity assay (positive) but there is not quantification of activity
  • アプリケーション

    Western blot

    SDS-PAGE

    Functional Studies

  • 精製度> 85 % SDS-PAGE.
    ab113187 is purified by multi-step chromatography.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.15% Glutathione, 99% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • DnaK type molecular chaperone HSP70 1
    • Epididymis secretory protein Li 103
    • FLJ54303
    • FLJ54370
    • FLJ54392
    • FLJ54408
    • FLJ75127
    • Heat shock 70 kDa protein 1
    • Heat shock 70 kDa protein 1/2
    • Heat shock 70 kDa protein 1A/1B
    • Heat shock 70kDa protein 1A
    • Heat shock 70kDa protein 1B
    • Heat shock induced protein
    • HEL S 103
    • HSP70 1
    • HSP70 1B
    • HSP70 2
    • HSP70-1/HSP70-2
    • HSP70-1A
    • HSP70.1
    • HSP70.1/HSP70.2
    • HSP70I
    • HSP71_HUMAN
    • HSP72
    • HSPA1
    • HSPA1A
    • HSPA1B
    see all
  • 機能In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
  • 組織特異性HSPA1B is testis-specific.
  • 配列類似性Belongs to the heat shock protein 70 family.
  • 細胞内局在Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt

Recombinant mouse Hsp70 protein 画像

  • SDS-PAGE showing ab113187 (1µg).
  • Lane 1: MWM
    Lane 2: 100 ng ab113187
    Lane 3: 50 ng E. coli DnaK Protein

    Left: probed with Hsp70 mAb at 1.0 µg/ml.
    Right: probed with DnaK mAb at 1.0 µg/ml.

Recombinant mouse Hsp70 protein (ab113187) 使用論文

ab113187 has not yet been referenced specifically in any publications.

Product Wall

This protein, ab113187, does not have a tag.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"