Recombinant mouse EPO protein (Fc Chimera) (ab170076)
Key features and details
- Expression system: Insect cells
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
製品の詳細
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製品名
Recombinant mouse EPO protein (Fc Chimera)
EPO タンパク質・ペプチド 製品一覧 -
生理活性
ED50 < 5 ng/ml as determined in a cell proliferation assay using Human TF-1 erythroleukemia cells.
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精製度
> 95 % SDS-PAGE.
ab170076 is purified by chromatography, sterile filtered and lyophilized. -
発現系
Insect cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Mouse -
配列
APPRLICDSRVLERYILEAKEAENVTMGCAEGPRLSENITVPDTKVNFYA WKRMEVEEQAIEVWQGLSLLSEAILQAQALLANSSQPPETLQLHIDKAIS GLRSLTSLLRVLGAQKELMSPPDTTPPAPLRTLTVDTFCKLFRVYANFLR GKLKLYTGEVCRRGDR -
予測される分子量
49 kDa -
領域
27 to 192
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特性
Our Abpromise guarantee covers the use of ab170076 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Functional Studies
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製品の状態
Lyophilized -
備考
Produced using non-baculovirus insect cells.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at -80°C.
pH: 7.4
Constituent: 100% PBSThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Add 0.5ml deionized water. Aliquot and freeze unused portion.
関連情報
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別名
- EP
- EPO
- EPO alpha
see all -
関連性
Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. -
細胞内局在
Secreted
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab170076 は 1 報の論文で使用されています。
- Ferrao RD et al. Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation. Elife 7:N/A (2018). PubMed: 30044226