Recombinant Mouse DLK protein (Fc fragment) (ab108574)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来HEK 293 cells
  • アミノ酸配列
    • アクセッション番号Q09163
    • 生物種Mouse
    • 分子量75 kDa
    • 領域1 to 305
    • 配列の追加情報Fused with the Fc region of Human IgG1 at the C-terminus.

特性

Our Abpromise guarantee covers the use of ab108574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 精製度> 90 % SDS-PAGE.
    ab108574 is 0.2µm filtered
  • 製品の状態Liquid
  • 備考Working aliquots are stable for up to 3 months when stored at -20°C. Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

関連情報

  • 別名
    • Adipocyte differentiation inhibitor protein
    • Brevideltin
    • Delta like 1 homolog
    • Delta like homolog
    • Delta like protein
    • Delta1
    • DLK
    • DLK 1
    • DLK-1
    • DLK1
    • DLK1_HUMAN
    • FA 1
    • FA1
    • Fetal antigen 1
    • pG2
    • Preadipocyte factor 1
    • Pref
    • Pref 1
    • Pref1
    • Protein delta homolog 1
    • Secredeltin
    • ZOG
    see all
  • 機能May have a role in neuroendocrine differentiation.
  • 組織特異性Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue.
  • 配列類似性Contains 6 EGF-like domains.
  • 翻訳後修飾N- and O-glycosylated.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant Mouse DLK protein (Fc fragment) 画像

  • Induction of SOX-9 with the treatment of recombinant mouse DLK-Fc (ab108574).
    A mouse preadpipocyte cell line, 3T3L1, was stimulated with 5µg/ml of ab108574 as in indicated time points and each cell lysate was prepared and subjected to western blot by using anti-rabbit Sox-9 and anti-rabbit GAPDH.

    1=0 min; 2=10 min; 3=30 min; 4=1 h; 5=2 h; 6=3 h; 7=4 h; 8=24 h.

     

Recombinant Mouse DLK protein (Fc fragment) (ab108574) 使用論文

ab108574 has not yet been referenced specifically in any publications.

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