製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Mouse
    • 配列
      NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLP
    • 領域
      27 to 114

特性

Our Abpromise guarantee covers the use of ab50221 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Functional Studies

  • エンドトキシン・レベル
    < 0.100 Eu/µg
  • 精製度
    > 95 % SDS-PAGE.

  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

  • 再構成
    Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

関連情報

  • 別名
    • C-X-C motif chemokine 16
    • Chemokine (C X C motif) ligand 16
    • Chemokine, CXC motif, ligand 16
    • CXC chemokine ligand 16
    • Cxcl16
    • CXCLG16
    • CXL16_HUMAN
    • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
    • SCYB16
    • Small inducible cytokine B16 precursor
    • Small-inducible cytokine B16
    • SR-PSOX
    • SRPSOX
    • Transmembrane chemokine CXCL16
    • UNQ2759/PRO6714
    see all
  • 機能
    Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
  • 組織特異性
    Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
  • 配列類似性
    Belongs to the intercrine alpha (chemokine CxC) family.
  • 翻訳後修飾
    Glycosylated.
  • 細胞内局在
    Cell membrane. Secreted. Also exists as a soluble form.
  • Information by UniProt

参考文献

ab50221 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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