The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
C5a is rapidly desarginated by serum carboxypeptidase N to the less potent derivate C5a desArg, the first stage in deactivation of anaphylatoxin activity. The C5a desArg form has a different spectrum of bioactivity to intact C5a.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
再構成Reconstitute the vial by injection of 0.5 ml distilled or de-ionised water. Store stock solution after reconstitution in aliquots at -20°C. Repeated freeze and thaw cycles cause loss of activity.
For dilutions use protein stabilized phosphate buffered saline, pH 7.4.
Anaphylatoxin C5a analog
Complement C5 precursor
Complement component 5
Complement component C5a
関連性C5 is involved in the activation of the lytic pathway within the complement system, which is an important factor in innate immunity.
Recombinant Mouse C5a / C5a des Arg protein (ab90892) 使用論文
has not yet been referenced specifically in any publications.