Recombinant mouse beta Defensin 3 protein (ab125742)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Mouse
    • 配列
      KKINNPVSCL RKGGRCWNRC IGNTRQIGSC GVPFLKCCKR K
    • 分子量
      5 kDa
    • 領域
      23 to 63

特性

Our Abpromise guarantee covers the use of ab125742 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 4-20µg/ml.
  • アプリケーション

    Functional Studies

    SDS-PAGE

    HPLC

  • 精製度
    > 98 % SDS-PAGE.
    ab125742 is purified by proprietary chromatographic techniques. Purity is greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    pH: 7.40
    Constituent: 99% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    It is recommended to reconstitute the ab125742 in sterile ultra pure water not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Upon reconstitution ab125742 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

関連情報

  • 別名
    • BD 3
    • BD-3
    • BD3
    • beta 103
    • Beta defensin 103A
    • Beta defensin 103A precursor
    • Beta defensin 3
    • Beta-defensin 103
    • Beta-defensin 3
    • D103A_HUMAN
    • DEF B3
    • DEFB 103
    • DEFB 103A
    • DEFB 3
    • DEFB-3
    • DEFB103
    • DEFB103A
    • DEFB103B
    • DEFB3
    • Defensin
    • Defensin beta 103A
    • Defensin beta 3
    • Defensin like protein
    • Defensin-like protein
    • HBD 3
    • hBD-3
    • HBD3
    • HBP 3
    • HBP3
    • mBD3
    see all
  • 機能
    Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
  • 組織特異性
    Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
  • 配列類似性
    Belongs to the beta-defensin family.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab125742 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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