The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 4-20µg/ml.
% SDS-PAGE. ab125742 is purified by proprietary chromatographic techniques. Purity is greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
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Shipped at 4°C. Store at -20°C. Store under desiccating conditions.
pH: 7.40 Constituent: 99% PBS
This product is an active protein and may elicit a biological response in vivo, handle with caution.
It is recommended to reconstitute the ab125742 in sterile ultra pure water not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Upon reconstitution ab125742 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Beta defensin 103A
Beta defensin 103A precursor
Beta defensin 3
Defensin beta 103A
Defensin beta 3
Defensin like protein
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.