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Our Abpromise guarantee covers the use of ab54483 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Determined by its ability to inhibit the proliferation of murine myeloid cell lines M1. The ED50 for this effect is ≤ 15 µg/ml.
gAcrp30 is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, gAcrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signalling muscle to absorb and burn Free-Fatty Acids (FFAs). The signalling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver. Recombinant mouse gAcrp30 (ab54483) is a 16.6 kDa protein consisting of 145 amino acid residues.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Endotoxin level: < 0.1 ng per µg of gAcrp30.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ab54483 has not yet been referenced specifically in any publications.