The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
エンドトキシン・レベル< 0.100 Eu/µg
備考The biological activity of this product is determined by its ability to chemoattract human eosinophils using a concentration range of 10.0-100.0 ng/ml.
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Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
C-C motif chemokine 13
Chemokine (C C motif) ligand 13
CK beta 10
Monocyte chemoattractant protein 4
Monocyte chemotactic protein 4
New CC chemokine 1
Small inducible cytokine A13 precursor
Small inducible cytokine subfamily A (Cys Cys) member 13
Small-inducible cytokine A13
機能Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
組織特異性Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
配列類似性Belongs to the intercrine beta (chemokine CC) family.
翻訳後修飾One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain.