Recombinant human WISP3 protein (ab50049)

製品の概要

  • 製品名Recombinant human WISP3 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列TGPLDTTPEG RPGEVSDAPQ RKQFCHWPCK CPQQKPRCPP GVSLVRDGCG CCKICAKQPG EICNEADLCD PHKGLYCDYS VDRPRYETGV CAYLVAVGCE FNQVHYHNGQ VFQPNPLFSC LCVSGAIGCT PLFIPKLAGS HCSGAKGGKK SDQSNCSLEP LLQQLSTSYK TMPAYRNLPL IWKKKCLVQA TKWTPCSRTC GMGISNRVTN ENSNCEMRKE KRLCYIQPCD SNILKTIKIP KGKTCQPTFQ LSKAEKFVFS GCSSTQSYKP TFCGICLDKR CCIPNKSKMI TIQFDCPNEG SFKWKMLWIT SCVCQRNCRE PGDIFSELKI L

関連製品

特性

Our Abpromise guarantee covers the use of ab50049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Biological Activity : The ED50 was determined by the dose-dependant proliferation of the MCF-7 cell line. The expected ED50 for this effect is 0.2-0.3 µg/ml.
  • アプリケーション

    SDS-PAGE

    Functional Studies

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • CCN 6
    • CCN family member 6
    • CCN6
    • CYR61
    • LIBC
    • Lost in inflammatory breast cancer tumor suppressor protein
    • MGC125987
    • MGC125988
    • MGC125989
    • OTTHUMP00000040421
    • PPAC
    • PPD
    • UNQ462/PRO790/PRO956
    • WISP 3
    • WISP-3
    • WISP3
    • WISP3_HUMAN
    • WNT 1 inducible signaling pathway protein 3
    • Wnt 1 signaling pathway protein 3
    • WNT1 inducible signaling pathway protein 3
    • WNT1 inducible signaling pathway protein 3 precursor
    • WNT1-inducible-signaling pathway protein 3
    see all
  • 機能Appears to be required for normal postnatal skeletal growth and cartilage homeostasis.
  • 組織特異性Predominant expression in adult kidney and testis and fetal kidney. Weaker expression found in placenta, ovary, prostate and small intestine. Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes.
  • 関連疾患Defects in WISP3 are the cause of progressive pseudorheumatoid arthropathy of childhood (PPAC) [MIM:208230]. PPAC is an autosomal recessive disorder characterized by stiffness and swelling of joints, motor weakness and joint contractures. Signs and symptoms of the disease develop typically between three and eight years of age. This progressive disease is a primary disorder of articular cartilage with continued cartilage loss and destructive bone changes with aging.
  • 配列類似性Belongs to the CCN family.
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
    Contains 1 IGFBP N-terminal domain.
    Contains 1 TSP type-1 domain.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant human WISP3 protein (ab50049) 使用論文

ab50049 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your telephone enquiry yesterday afternoon. I can confirm that our ab50049 WISP3 human protein (Active) has been tested for biological activity in cell culture, so it will be covered by our guarantee for this application. The orig...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"