製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P61962
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMVYAMNWSVRPDKRFRLALGSFVEEYNNKV QLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRV WRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTI WGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGA DGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEV VILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWD
    • 分子量34 kDa
    • 領域19 to 295
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab111624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab111624 was denatured using detergent during conventional chromatography purification process.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 2.4% Urea

関連情報

  • 別名
    • AN11
    • Dcaf7
    • DCAF7_HUMAN
    • DDB1- and CUL4-associated factor 7
    • HAN11
    • Human anthocyanin
    • Petunia
    • Seven WD repeat protein of the AN11 family 1
    • SWAN 1
    • WD repeat domain 68
    • WD repeat protein An11 homolog
    • WD repeat-containing protein 68
    • WD repeat-containing protein An11 homolog
    • WDR68
    see all
  • 機能Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Belongs to the WD repeat DCAF7 family.
    Contains 4 WD repeats.
  • 細胞内局在Cytoplasm. Nucleus. Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm.
  • Information by UniProt

Recombinant Human WDR68 protein 画像

  • 15% SDS-PAGE showing ab111624 at approximately 33.6kDa (3µg).

Recombinant Human WDR68 protein (ab111624) 使用論文

ab111624 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"