製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MGSHMMLVLV LGDLHIPHRC NSLPAKFKKL LVPGKIQHIL CTGNLCTKES YDYLKTLAGD VHIVRGDFDE NLNYPEQKVV TVGQFKIGLI HGHQVIPWGD MASLALLQRQ FDVDILISGH THKFEAFEHE NKFYINPGSA TGAYNALETN IIPSFVLMDI QASTVVTYVY QLIGDDVKVE RIEYKKP
    • 分子量
      23 kDa including tags
    • 領域
      1 to 182
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab124582 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab124582 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride

関連情報

  • 別名
    • DC15
    • DC7
    • DKFZp564F0223
    • FLJ20492
    • hVPS29
    • PEP11
    • PEP11 homolog
    • Retromer protein
    • Vacuolar protein sorting 29
    • Vacuolar protein sorting 29 (yeast homolog)
    • Vacuolar protein sorting 29 (yeast)
    • Vacuolar protein sorting 29 homolog
    • Vacuolar protein sorting 29 homolog (S. cerevisiae)
    • Vacuolar protein sorting associated protein 29
    • Vacuolar protein sorting-associated protein 29
    • Vacuolar sorting protein VPS29/PEP11
    • Vesicle protein sorting 29
    • VPS 29
    • VPS29
    • VPS29 retromer complex component
    • VPS29_HUMAN
    • x 007 protein
    see all
  • 機能
    Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).
  • 組織特異性
    Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.
  • 配列類似性
    Belongs to the VPS29 family.
  • 細胞内局在
    Cytoplasm. Membrane. Endosome membrane.
  • Information by UniProt

画像

  • 15% SDS-PAGE showing ab124582 at approximately 23.2kDa (3µg).

参考文献

ab124582 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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