製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q9BRG1
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MGSHMAMSFE WPWQYRFPPF FTLQPNVDTR QKQLAAWCSL VLSFCRLHKQ SSMTVMEAQE SPLFNNVKLQ RKLPVESIQI VLEELRKKGN LEWLDKSKSS FLIMWRRPEE WGKLIYQWVS RSGQNNSVFT LYELTNGEDT EDEEFHGLDE ATLLRALQAL QQEHKAEIIT VSDGRGVKFF
    • 分子量23 kDa including tags
    • 領域1 to 200
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab124321 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 85 % SDS-PAGE.
    ab124321 was purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • Dermal papilla derived protein 9
    • Dermal papilla-derived protein 9
    • DERP9
    • EAP20
    • ELL associated protein of 20 kDa
    • ELL-associated protein of 20 kDa
    • ESCRT-II complex subunit VPS25
    • FAP20
    • HGNC:28122
    • hVps25
    • MGC10540
    • Vacuolar protein sorting 25 homolog (S. cerevisiae)
    • Vacuolar protein sorting associated protein 25
    • Vacuolar protein-sorting-associated protein 25
    • VPS25
    • VPS25_HUMAN
    see all
  • 機能Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.
  • 組織特異性Expressed at the mRNA level in kidney, liver, pancreas, and placenta. Lower levels of expression are found in heart, skeletal muscle, brain and lung.
  • 配列類似性Belongs to the VPS25 family.
  • 細胞内局在Cytoplasm. Endosome membrane. Nucleus > nucleoplasm. Distributes diffusely throughout the cytoplasm and nucleoplasm, but exhibits a punctate distribution on coexpression with CHMP6.
  • Information by UniProt

Recombinant Human VPS25 protein 画像

  • ab124321 (VPS25 protein), at 3 µg, analyzed by 15% SDS-PAGE.

Recombinant Human VPS25 protein (ab124321) 使用論文

ab124321 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab124321.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"