Recombinant human VEGF Receptor 1 protein (ab84771)

製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Insect cells
  • アミノ酸配列
    • 生物種Human
    • 領域784 to 1338

関連製品

特性

Our Abpromise guarantee covers the use of ab84771 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性The Specific activity of ab84771 was determined to be 35 nmol/min/mg.
  • アプリケーション

    Western blot

    Functional Studies

    SDS-PAGE

  • 製品の状態Liquid
  • 備考

    ab204862 (IRS1 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • EC 2.7.10.1
    • FLT
    • FLT 1
    • Flt-1
    • FLT1
    • Fms like tyrosine kinase 1
    • Fms related tyrosine kinase 1
    • Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
    • Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor
    • Fms-like tyrosine kinase 1
    • FRT
    • Soluble VEGF receptor 1 14
    • Soluble VEGFR1 variant 2
    • Soluble VEGFR1 variant 21
    • Tyrosine protein kinase FRT
    • Tyrosine protein kinase receptor FLT
    • Tyrosine-protein kinase FRT
    • Tyrosine-protein kinase receptor FLT
    • Vascular endothelial growth factor receptor 1
    • Vascular endothelial growth factor vascular permeability factor receptor
    • Vascular permeability factor receptor
    • Vascular permeability factor receptor 1
    • VEGFR 1
    • VEGFR-1
    • VEGFR1
    • VGFR1_HUMAN
    see all
  • 機能Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
  • 組織特異性Mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. Specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. Isoform sFlt1 is strongly expressed in placenta.
  • 配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • 細胞内局在Secreted and Cell membrane.
  • Information by UniProt

Recombinant human VEGF Receptor 1 protein 画像

  • The Specific activity of ab84771 was determined to be 35 nmol/min/mg.
  • SDS-PAGE showing ab84771 at approximately 94kDa.

Recombinant human VEGF Receptor 1 protein (ab84771) 使用論文

ab84771 has not yet been referenced specifically in any publications.

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