製品の概要
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製品名Recombinant Human VCAM1 protein
VCAM1 タンパク質・ペプチド 製品一覧 -
タンパク質長Full length protein
製品の詳細
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由来Recombinant
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由来Escherichia coli
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アミノ酸配列
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生物種Human
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領域25 to 698
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab55238 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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精製度> 95 % SDS-PAGE.
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製品の状態Liquid
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Preservative: None
Constituents: 50% Glycerol, PBS, pH 7.4
関連情報
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別名
- CD106
- CD106 Antigen
- INCAM 100
see all -
機能Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
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組織特異性Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
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配列類似性Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
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ドメインEither the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
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翻訳後修飾Sialoglycoprotein.
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細胞内局在Membrane.
- Information by UniProt
画像
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SDS-PAGE - VCAM1 protein (His tag) (ab55238)ab55238 on SDS-PAGE
参考文献
ab55238 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"