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別名
- Amine oxidase copper containing 3
- AOC3
- AOC3_HUMAN
- Copper amine oxidase
- HPAO
- Membrane primary amine oxidase
- Semicarbazide-sensitive amine oxidase
- SSAO
- VAP-1
- VAP1
- Vascular adhesion protein 1
see all
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機能
Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.
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組織特異性
Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis.
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配列類似性
Belongs to the copper/topaquinone oxidase family.
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翻訳後修飾
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
N- and O-glycosylated.
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細胞内局在
Membrane.
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Information by UniProt