製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 分子量
      24 kDa
    • 領域
      48 to 255
    • タグ
      His-DHFR tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab125983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • 再構成
    Reconstitute with water to desired concentration.

関連情報

  • 別名
    • Deubiquitinating enzyme
    • Deubiquitinating enzyme 15
    • EC 3 1 2 15
    • KIAA0529
    • MGC131982
    • MGC149838
    • MGC74854
    • Ubiquitin Carboxy terminal Hydrolase 15
    • Ubiquitin carboxyl-terminal hydrolase 15
    • Ubiquitin specific peptidase 15
    • Ubiquitin specific processing protease 15
    • Ubiquitin Specific Protease 15
    • Ubiquitin thioesterase 15
    • Ubiquitin thiolesterase 15
    • Ubiquitin-specific-processing protease 15
    • UBP 15
    • UBP15
    • UBP15_HUMAN
    • Unph 2
    • UNPH 4
    • Unph-2
    • Unph2
    • Unph4
    • USP 15
    • Usp15
    see all
  • 機能
    Protease that degrades 'Lys-48'-linked polyubiquitin chains. Protects target proteins against proteasomal degradation. Protects APC and human papillomavirus type 16 protein E6 against degradation via the ubiquitin proteasome pathway.
  • 組織特異性
    Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues.
  • 配列類似性
    Belongs to the peptidase C19 family.
    Contains 1 DUSP domain.
  • 翻訳後修飾
    Phosphorylated. Phosphorylation protects against ubiquitination and subsequent degradation by the proteasome.
    Ubiquitinated, leading to degradation by the proteasome.
  • Information by UniProt

参考文献

ab125983 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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