Recombinant Human Uroplakin III protein (ab115705)

製品の概要

  • 製品名
    Recombinant Human Uroplakin III protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMGSHMVNLQPQLASVTFATNNPTLTTVALE KPLCMFDSKEALTGTHEVYLYVLVDSAISRNASVQDSTNTPLGSTFLQTE GGRTGPYKAVAFDLIPCSDLPSLDAIGDVSKASQILNAYLVRVGANGTCL WDPNFQGLCNPPLSAATEYRFKYVLVNMSTGLVEDQTLWSDPIRTNQLTP YSTIDTWPGRRSGG
    • 分子量
      23 kDa including tags
    • 領域
      19 to 207
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab115705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Mass Spectrometry

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab115705 is purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.03% DTT, 20% Glycerol, 0.88% Sodium chloride

関連情報

  • 別名
    • MGC119178
    • OTTHUMP00000028951
    • UP III
    • UP3a
    • UPIII
    • UPIIIA
    • UPK 3
    • UPK 3A
    • UPK3
    • UPK3A
    • UPK3A_HUMAN
    • Uroplakin 3A
    • Uroplakin III
    • Uroplakin-3a
    • Uroplakin3A
    • UroplakinIII
    see all
  • 機能
    Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.
  • 組織特異性
    Expressed in ureter.
  • 関連疾患
    Defects in UPK3A are a cause of renal adysplasia (RADYS) [MIM:191830]; also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy.
  • 配列類似性
    Belongs to the uroplakin-3 family.
  • 細胞内局在
    Endoplasmic reticulum membrane. Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
  • Information by UniProt

画像

  • 15% SDS-PAGE showing ab115705 at approximately 23.1kDa (3µg).

参考文献

ab115705 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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