製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      GTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLT
    • 領域
      181 to 214

特性

Our Abpromise guarantee covers the use of ab79512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    ELISA

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.

  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 1X PBS

  • 再構成
    Re-dissolve the powder with 1ml sterile water to give 1mg/ml.

関連情報

  • 別名
    • Mitochondrial uncoupling protein 3
    • SLC25A9
    • Solute carrier family 25 member 9
    • UCP 3
    • UCP3
    • UCP3_HUMAN
    • Uncoupling protein 3
    • Uncoupling protein 3 mitochondrial proton carrier
    see all
  • 機能
    UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.
  • 組織特異性
    Only in skeletal muscle and heart. Is more expressed in glycolytic than in oxidative skeletal muscles.
  • 関連疾患
    Defects in UCP3 may be involved in obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • 配列類似性
    Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • 細胞内局在
    Mitochondrion inner membrane.
  • Information by UniProt

画像

  • 20% SDS PAGE gel. Commassie blue staining.

参考文献

ab79512 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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