Recombinant Human UBE2D2 protein (Chemical Free) (ab81575)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • タグproprietary tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab81575 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Conjugation

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Lyophilised
  • 備考

    UbcH5b has 89% and 88% sequence identity with UbcH5a and UbcH5c respectively.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM HEPES, 100mM Sodium chloride, pH 8.0

関連情報

  • 別名
    • E2(17)KB2
    • OTTHUMP00000223475
    • OTTHUMP00000223476
    • OTTHUMP00000223477
    • OTTHUMP00000223478
    • OTTHUMP00000224375
    • PUBC 1
    • PUBC1
    • UB2D2_HUMAN
    • UBC 4
    • UBC 4/5
    • UBC4
    • UBC4/5
    • UBC4/5 homolog yeast
    • UBCH 5B
    • UBCH5B
    • UBE2D2
    • Ubiquitin carrier protein
    • Ubiquitin carrier protein D2
    • Ubiquitin conjugating enzyme E2 17 kDa 2
    • Ubiquitin conjugating enzyme E2 D2
    • Ubiquitin conjugating enzyme E2D 2
    • Ubiquitin conjugating enzyme E2D 2 (homologous to yeast UBC4/5)
    • Ubiquitin conjugating enzyme E2D 2 (UBC4/5 homolog yeast)
    • Ubiquitin protein ligase D2
    • Ubiquitin-conjugating enzyme E2 D2
    • Ubiquitin-conjugating enzyme E2(17)KB 2
    • Ubiquitin-conjugating enzyme E2-17 kDa 2
    • Ubiquitin-protein ligase D2
    see all
  • 機能Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Belongs to the ubiquitin-conjugating enzyme family.
  • Information by UniProt

Recombinant Human UBE2D2 protein (Chemical Free) (ab81575) 使用論文

ab81575 has not yet been referenced specifically in any publications.

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