Recombinant Human UBE2D1 protein (Chemical Free) (ab81580)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • タグproprietary tag N-Terminus

関連製品

特性

Our Abpromise guarantee covers the use of ab81580 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Conjugation

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Lyophilised
  • 備考

     Ubch5a has 89% and 88% sequence identity with Ubch5b and Ubch5c respectively. Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM HEPES, 100mM Sodium chloride, 1mM DTT, pH 8.0

関連情報

  • 別名
    • E2(17)KB1
    • SFT
    • Stimulator of Fe transport
    • UB2D1_HUMAN
    • UBC 4/5
    • UBC4/5
    • UBC4/5 homolog
    • UBC4/5, S. cerevisiae, homolog of
    • UBCH 5
    • UBCH 5A
    • UbcH5
    • UBCH5A
    • Ube2d1
    • Ubiquitin carrier protein
    • Ubiquitin carrier protein D1
    • Ubiquitin conjugating enzyme E2 17 kDa 1
    • Ubiquitin conjugating enzyme E2 D1
    • Ubiquitin conjugating enzyme E2D 1
    • Ubiquitin conjugating enzyme E2D 1 (UBC4/5 homolog yeast)
    • Ubiquitin conjugating enzyme UBCH5A
    • Ubiquitin protein ligase D1
    • Ubiquitin-conjugating enzyme E2 D1
    • Ubiquitin-conjugating enzyme E2(17)KB 1
    • Ubiquitin-conjugating enzyme E2-17 kDa 1
    • Ubiquitin-protein ligase D1
    see all
  • 機能Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of CHIP, TRAF6 and TRIM63/MURF1. Ubiquitinates CHIP-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
  • 組織特異性Ubiquitous. Up-regulated in livers of iron-overloaded patients with hereditary hemochromatosis.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Belongs to the ubiquitin-conjugating enzyme family.
  • 細胞内局在Cytoplasm.
  • Information by UniProt

Recombinant Human UBE2D1 protein (Chemical Free) (ab81580) 使用論文

ab81580 has not yet been referenced specifically in any publications.

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