製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q8TBC4
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MGSHMADGEE PERKRRRIEE LLAEKMAVDG GCGDTGDWEG RWNHVKKFLE RSGPFTHPDF EPSTESLQFL LDTCKVLVIG AGGLGCELLK NLALSGFRQI HVIDMDTIDV SNLNRQFLFR PKDIGRPKAE VAAEFLNDRV PNCNVVPHFN KIQDFNDTFY RQFHIIVCGL DSIIARRWIN GMLISLLNYE DGVLDPSSIV PLIDGGTEGF KGNARVILPG MTACIECTLE LYPPQVNFPM CTIASMPRLP EHCIEYVRML QWPKEQPFGE GVPLDGDDPE HIQWIFQKSL ERASQYNIRG VTYRLTQGVV KRIIPAVAST NAVIAAVCAT EVFKIATSAY IPLNNYLVFN DVDGLYTYTF EAERKENCPA CSQLPQNIQF SPSAKLQEVL DYLTNSASLQ MKSPAITATL EGKNRTLYLQ SVTSIEERTR PNLSKTLKEL GLVDGQELAV ADVTTPQTVL FKLHFTS
    • 分子量54 kDa including tags
    • 領域1 to 463
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab123194 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol

関連情報

  • 別名
    • DKFZp566J164
    • EC 6.3.2.
    • hUba3
    • MGC22384
    • NEDD8 activating enzyme E1 catalytic subunit
    • NEDD8 activating enzyme E1C
    • Nedd8 activating enzyme hUba3
    • NEDD8-activating enzyme E1 catalytic subunit
    • NEDD8-activating enzyme E1C
    • uba3
    • UBA3 ubiquitin activating enzyme E1 homolog
    • UBA3_HUMAN
    • UBE1C
    • Ubiquitin activating enzyme 3
    • Ubiquitin activating enzyme E1C
    • Ubiquitin-activating enzyme 3
    • Ubiquitin-activating enzyme E1C
    • Ubiquitin-like modifier-activating enzyme 3
    see all
  • 機能Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.
  • 組織特異性Ubiquitously expressed.
  • パスウェイProtein modification; protein neddylation.
  • 配列類似性Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
  • Information by UniProt

Recombinant Human UBE1C protein 画像

  • 15% SDS-PAGE showing ab123194 (3µg).

Recombinant Human UBE1C protein (ab123194) 使用論文

ab123194 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"