製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG
    • 分子量
      16 kDa including tags
    • 領域
      1 to 122
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab119156 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol

関連情報

  • 別名
    • 2010003O14Rik
    • CGI 135
    • CGI135
    • FIS 1
    • FIS1
    • Fis1 homolog
    • FIS1, S. cerevisiae, homolog of
    • FIS1_HUMAN
    • Fission 1 (mitochondrial outer membrane) homolog
    • Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
    • Fission 1 (mitochondrial outer membrane) homolog (yeast)
    • Fission 1 homolog
    • H NH0132A01.6
    • hFis 1
    • hFis1
    • Mitochondrial fission 1 protein
    • mitochondrial fission molecule
    • Tetratricopeptide repeat domain 11
    • Tetratricopeptide repeat protein 11
    • TPR repeat protein 11
    • TTC 11
    see all
  • 機能
    Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
  • 配列類似性
    Belongs to the FIS1 family.
    Contains 1 TPR repeat.
  • ドメイン
    The C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
  • 翻訳後修飾
    Ubiquitinated by MARCH5.
  • 細胞内局在
    Mitochondrion outer membrane. Peroxisome membrane.
  • Information by UniProt

参考文献

ab119156 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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