製品の概要

法規制情報

製品の詳細

  • 由来
    Recombinant
  • 由来
    Baculovirus infected Sf9 cells
  • アミノ酸配列
    • 生物種
      Human

関連製品

特性

Our Abpromise guarantee covers the use of ab70075 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.

  • 製品の状態
    Liquid
  • 備考

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • DGS-G
    • DGSG
    • DiGeorge syndrome protein G
    • Serine/threonine kinase 22B (spermiogenesis associated)
    • Serine/threonine protein kinase 22B
    • Serine/threonine-protein kinase 22B
    • Spermiogenesis associated 2
    • SPOGA2
    • STK22B
    • Testis specific kinase 2
    • Testis specific serine kinase 2
    • Testis specific serine threonine kinase 2
    • Testis specific serine/threonine protein kinase 2
    • Testis-specific kinase 2
    • Testis-specific serine/threonine-protein kinase 2
    • TSK 2
    • TSK-2
    • TSK2
    • TSSK 2
    • TSSK-2
    • Tssk2
    • TSSK2_HUMAN
    see all
  • 機能
    Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
  • 組織特異性
    Testis-specific. Present in mature spermatozoa (at protein level).
  • 配列類似性
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • 翻訳後修飾
    Autophosphorylated.
  • 細胞内局在
    Cytoplasm. Cytoplasm > cytoskeleton > centrosome > centriole. Present in the cytoplasm of elongating spermatids. In spermatozoa, localizes in the equatorial segment, neck, the midpiece and in a specific sperm head compartment (By similarity). In spermatids, concentrates in centrioles during flagellogenesis.
  • Information by UniProt

画像

  • Kinase activity assay of ab70075. The specific activity of TSSK2 was determined to be 136 nmol/min/mg.
  • SDS-PAGE of ab70075. Molecular weight 66kDa.

参考文献

ab70075 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab70075.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録