Recombinant human TRAIL protein (ab55764)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab55764 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Biological Activity: Determined by its ability to induce apoptotic cell death in TRAIL-sensitive U343MG cells. The expected ED50 for this effect is 1.0-3.0 ng/ml.
  • アプリケーション

    SDS-PAGE

    Functional Studies

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    Preservative: None

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted in water or other buffer solutions. Reconstituted protein should be stored in working aliquots at -20°C.

関連情報

  • 別名
    • Apo 2 ligand
    • APO 2L
    • Apo-2 ligand
    • Apo-2L
    • APO2L
    • CD253
    • CD253 antigen
    • Chemokine tumor necrosis factor ligand superfamily member 10
    • Protein TRAIL
    • TL2
    • TNF Related Apoptosis Inducing Ligand
    • TNF related apoptosis inducing ligand TRAIL
    • TNF-related apoptosis-inducing ligand
    • TNF10_HUMAN
    • TNFSF10
    • TRAIL
    • Tumor necrosis factor (ligand) family member 10
    • Tumor Necrosis Factor (ligand) Superfamily Member 10
    • Tumor necrosis factor apoptosis inducing ligand splice variant delta
    • Tumor necrosis factor ligand superfamily member 10
    see all
  • 機能Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
  • 組織特異性Widespread; most predominant in spleen, lung and prostate.
  • 配列類似性Belongs to the tumor necrosis factor family.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant human TRAIL protein (ab55764) 使用論文

ab55764 has not yet been referenced specifically in any publications.

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I am sorry to confirm that non of these peptides have been tested in Western blot. All tested applications covered by the 6 month guarantee are listed on the individual product datasehets.

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I have attached the data for the Functional Studies done with ab2219. We will add these to the datasheet as well very soon.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"