製品の概要

  • 製品名Recombinant Human TPM4 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P67936
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MAGLNSLEAV KRKIQALQQQ ADEAEDRAQG LQRELDGERE RREKAEGDVA ALNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE EADRKYEEVA RKLVILEGEL ERAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE KEDKYEEEIK LLSDKLKEAE TRAEFAERTV AKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ TLNELNCI
    • 分子量31 kDa
    • 領域1 to 248
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab105576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF-TOF
  • 精製度> 85 % SDS-PAGE.
    ab105576 was purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, pH 8

関連情報

  • 別名
    • epididymis secretory protein Li 108
    • HEL-S-108
    • TM30p1
    • TMP 4
    • TPM4
    • TPM4_HUMAN
    • Tropomyosin 4
    • Tropomyosin alpha 4 chain
    • Tropomyosin alpha-4 chain
    • Tropomyosin-4
    • wu:fb06e07
    • zgc:103436
    • zgc:63909
    see all
  • 機能Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
  • 組織特異性Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level).
  • 配列類似性Belongs to the tropomyosin family.
  • ドメインThe molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
  • 細胞内局在Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human TPM4 protein 画像

  • 15% SDS-PAGE analysis of ab105576 (3ug)

Recombinant Human TPM4 protein (ab105576) 使用論文

ab105576 has not yet been referenced specifically in any publications.

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