製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q9BUP3
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMAETEALSKLREDFRMQNKSVFILGASGET GRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQEVVDFEKLDDYAS AFQGHDVGFCCLGTTRGKAGAEGFVRVDRDYVLKSAELAKAGGCKHFNLL SSKGADKSSNFLYLQVKGEVEAKVEELKFDRYSVFRPGVLLCDRQESRPG EWLVRKFFGSLPDSWARGHSVPVVTVVRAMLNNVVRPRDKQMELLENKAI HDLGKAHGSLKP
    • 分子量29 kDa including tags
    • 領域1 to 242
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab117665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab117665 is purified by proprietary chromatographic techniques.
  • 製品の状態Liquid
  • 備考Although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 20% Glycerol

関連情報

  • 別名
    • 30 kDa HIV 1 TAT interacting protein
    • 30 kDa HIV-1 TAT-interacting protein
    • 30 kDa HIV1 TAT interacting protein
    • CC3
    • FLJ26963
    • HIV 1 Tat interacting protein 2
    • HIV 1 Tat interacting protein 2 30kDa
    • HIV-1 TAT-interactive protein 2
    • HTAI2_HUMAN
    • HTATIP 2
    • HTATIP2
    • Oxidoreductase HTATIP2
    • SDR44U1
    • Short chain dehydrogenase/reductase family 44U member 1
    • Tat interacting protein (30kDa)
    see all
  • 機能Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
  • 組織特異性Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas.
  • ドメインUnique C-terminus confers high proteasome-dependent instability to isoform 2.
  • 細胞内局在Cytoplasm. Nucleus envelope.
  • Information by UniProt

Recombinant Human TIP30 protein (ab117665) 使用論文

ab117665 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"