製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q9NQ88
    • 生物種Human
    • 配列ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKF THAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALS ELRAMAKAAREECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKE QFSQGSPSNCLETSLAEIFPLGKNHSSKVNSDSGIPGLAASVLVVSHGAY MRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIINFEEGREVKPT VQCICMNLQDHLNGLTETRGGGYGRKKRRQRRR
    • 分子量36 kDa including tags
    • 領域1 to 270

特性

Our Abpromise guarantee covers the use of ab115509 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Functional Studies

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 精製度> 95 % SDS-PAGE.
    ab115509 is greater than 95% by SDS-PAGE gel and HPLC analyses.
  • 製品の状態Lyophilised
  • 備考Pretreatment with ab115509 for 4 hrs, using a concentration range 0.1-5.0 µg/ml, protects U2OS cells from apoptosis induced by hydrogen peroxide.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

関連情報

  • 別名
    • 6-bisphosphatase TIGAR
    • C12ORF5
    • chromosome 12 open reading frame 5
    • FR2BP
    • Fructose-2,6-bisphosphatase TIGAR
    • Fructose-2,6-bisphosphate 2-phosphatase
    • Probable fructose 2,6 bisphosphatase TIGAR
    • Probable fructose-2
    • tigar
    • TIGAR_HUMAN
    • TP53 induced glycolysis and apoptosis regulator
    • TP53 induced glycolysis regulatory phosphatase
    • TP53-induced glycolysis and apoptosis regulator
    • Transactivated by NS3TP2 protein
    see all
  • 機能Probable fructose-biphosphatase. Lowers cellular levels of fructose 2,6-bisphosphate. Protects cells against reactive oxygen species and against apoptosis induced by p53/TP53.
  • 配列類似性Belongs to the phosphoglycerate mutase family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt

Recombinant Human TIGAR protein (ab115509) 使用論文

ab115509 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"