Recombinant Human Thymidine Phosphorylase protein (ab101169)

製品の概要

  • 製品名Recombinant Human Thymidine Phosphorylase protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P19971
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMAPPAPGDFSGEGSQGLPDPSPEPKQLPEL IRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETS VLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCK VPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSE QLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGA AVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEE ALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSA LGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTV ELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLR VHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPPQQ
    • 分子量51 kDa including tags
    • 領域11 to 482
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab101169 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab101169 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • ECGF
    • ECGF 1
    • ECGF1
    • Endothelial cell growth factor 1
    • Endothelial cell growth factor 1 platelet derived
    • Endothelial cell growth factor, platelet-derived
    • Gliostatin
    • hPD ECGF
    • MEDPS1
    • MNGIE
    • MTDPS1
    • PD ECGF
    • PD-ECGF
    • PDECGF
    • PDEGF
    • Platelet derived endothelial cell growth factor
    • Platelet derived endothelial growth factor
    • Platelet-derived endothelial cell growth factor
    • TdRPase
    • Thymidine phosphorylase
    • TP
    • Tymp
    • TYPH_HUMAN
    see all
  • 機能May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro.
    Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
  • パスウェイPyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2.
  • 関連疾患Mitochondrial DNA depletion syndrome 1 (MTDPS1) [MIM:603041]: A multisystem disease associated with mitochondrial dysfunction. It is clinically characterized by onset between the second and fifth decades of life, ptosis, progressive external ophthalmoplegia, gastrointestinal dysmotility (often pseudoobstruction), diffuse leukoencephalopathy, cachexia, peripheral neuropathy, and myopathy. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 配列類似性Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
  • Information by UniProt

Recombinant Human Thymidine Phosphorylase protein 画像

  • 15% SDS-PAGE showing ab101169 at approximately 51.3kDa (3µg).

Recombinant Human Thymidine Phosphorylase protein (ab101169) 使用論文

ab101169 has not yet been referenced specifically in any publications.

Product Wall



The endotoxins have not been removed, but the lab has tested the protein and the endotoxin level is low, ie. 0.37 EU/ug (determined by LAL method).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"