Recombinant human TGF beta 3 protein (ab52313)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
    • 分子量25 kDa
    • 領域301 to 412

特性

Our Abpromise guarantee covers the use of ab52313 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性TGF beta 3 is fully biologically active when compared to standard. The ED50 determined by cytotoxicity assay using the world health organization standard 98/608 as a direct comparison is <0.05 ng/ml, corresponding to a specific activity of >2 x 108 units/mg.
  • アプリケーション

    Western blot

    Functional Studies

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    >99% by SDS-PAGE and HPLC analyses
  • 製品の状態Liquid
  • 備考This protein solution should be stored at 4°C, stable for at least 3 months. For long term storage, it is recommended to add a carrier protein (0.1% HAS or BSA).
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C.

    Preservative: None
    Constituents: 20% Ethanol and 0.1% Acetate.
    Endotoxin level is <0.1 ng per µg.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • ARVD
    • ARVD1
    • FLJ16571
    • MGC105479
    • MGC118722
    • prepro-transforming growth factor beta-3
    • RNHF
    • TGF beta 3
    • TGF beta3
    • TGF-beta-3
    • TGFB 3
    • Tgfb3
    • TGFB3_HUMAN
    • transforming growth factor beta 3
    • Transforming growth factor beta-3
    see all
  • 機能Involved in embryogenesis and cell differentiation.
  • 関連疾患Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
  • 配列類似性Belongs to the TGF-beta family.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant human TGF beta 3 protein 画像

  • Anti-TGF beta 3 antibody (ab15537) at 1/200 dilution + Recombinant human TGF beta 3 protein (ab52313) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 30 seconds

Recombinant human TGF beta 3 protein (ab52313) 使用論文

ab52313 has not yet been referenced specifically in any publications.

Product Wall

The composition of the storage buffer of the ab52313 is 20% Ethanol and 0.1% Acetate.
Since there is 20% ethanol in the solution, hopefully the protein might not be fully frozen at -20C. Therefore, there is a possibility that the protein still wor...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"