製品の概要

  • 製品名Recombinant Human TFB1M protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q8WVM0
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMQAAKQLSQNFLLDLRLTDKIVRKAGNLTN AYVYEVGPGPGGITRSIL NADVAELLVVEKDTRFIPGLQMLSDAAPGK LRIVHGDVLTFKVEKAFSESLKRPWEDDPPNVHIIGNLPFSVSTP LII KWLENISCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLSVMAQY LCNVRHIFTIPGQAFVPKPEVD VGVVHFTPLIQPKIEQPFKLVEKVVQ NVFQFRRKYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISH FKSLCDVYRKMCDEDPQLFAYNFREELKRRKSKNEEKEEDDAENYRL
    • 分子量39 kDa including tags
    • 領域28 to 346
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113141 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab113141 was purified using conventional chromatography.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT

関連情報

  • 別名
    • CGI75
    • Dimethyladenosine transferase 1, mitochondrial
    • h-mtTFB
    • h-mtTFB1
    • hmtTFB
    • hmtTFB1
    • hTFB1M
    • Mitochondrial 12S rRNA dimethylase 1
    • Mitochondrial dimethyladenosine transferase 1
    • Mitochondrial transcription factor B1
    • mtTFB1
    • N'-adenosyl(rRNA) dimethyltransferase 1
    • S-adenosylmethionine-6-N'
    • Tfb1m
    • TFB1M_HUMAN
    • Transcription factor B1 mitochondrial
    see all
  • 機能S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.
  • 組織特異性Ubiquitously expressed.
  • 関連疾患Note=Variations in TFB1M may influence the clinical expression of aminoglycoside-induced deafness caused by the A1555G mutation in the mitochondrial 12S rRNA.
  • 配列類似性Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
  • 細胞内局在Mitochondrion.
  • Information by UniProt

Recombinant Human TFB1M protein 画像

  • 15% SDS-PAGE analysis of ab113141 (3µg)

Recombinant Human TFB1M protein (ab113141) 使用論文

ab113141 has not yet been referenced specifically in any publications.

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