Recombinant Human Syntenin protein (ab101950)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMSLYPSLEDLKVDKVIQAQTAFSANPANPA ILSEASAPIPHDGNLYPRLYPELSQYMGLSLNEEEIRANVAVVSGAPLQG QLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLK SIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARN GLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIK RMAPSIMKSLMDHTIPEV
    • 分子量
      35 kDa including tags
    • 領域
      1 to 298
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab101950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab101950 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 40% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, pH 8.0

関連情報

  • 別名
    • MDA-9
    • MDA9
    • Melanoma differentiation-associated protein 9
    • Pro-TGF-alpha cytoplasmic domain-interacting protein 18
    • Scaffold protein Pbp1
    • SDCB1_HUMAN
    • SDCBP
    • ST1
    • SYCL
    • Syndecan binding protein (syntenin)
    • Syndecan binding protein 1
    • Syndecan-binding protein 1
    • Syntenin 1
    • Syntenin-1
    • TACIP18
    see all
  • 機能
    Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
  • 組織特異性
    Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.
  • 配列類似性
    Contains 2 PDZ (DHR) domains.
  • 翻訳後修飾
    Phosphorylated on tyrosine residues.
  • 細胞内局在
    Cell junction > focal adhesion. Cell junction > adherens junction. Cell membrane. Endoplasmic reticulum membrane. Nucleus. Melanosome. Cytoplasm > cytosol. Cytoplasm > cytoskeleton. Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

Recombinant Human Syntenin protein 画像

  • 15% SDS-PAGE analysis of 3µg ab101950.

Recombinant Human Syntenin protein (ab101950) 使用論文

ab101950 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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