Recombinant Human Synaptotagmin V protein (ab91737)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      LLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFD RFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSL RYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKT TIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRV AVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP (Amin o acid sequence (Sequence determined by 5' Sequencing))
    • 領域
      152 to 386

特性

Our Abpromise guarantee covers the use of ab91737 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Mass Spectrometry

    SDS-PAGE

  • 製品の状態
    Lyophilised
  • 備考
    Protein Identity confirmed by Mass Spectrometry (MS/MS) (acquired on initial reference batch).
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5

  • 再構成
    Reconstitute with 96 µl aqua dest.

関連情報

  • 別名
    • Synaptotagmin 5
    • Synaptotagmin IX
    • Synaptotagmin V
    • Synaptotagmin-5
    • Syt5
    • SYT5_HUMAN
    • SytV
    see all
  • 機能
    May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface.
  • 配列類似性
    Belongs to the synaptotagmin family.
    Contains 2 C2 domains.
  • 細胞内局在
    Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Recycling endosome membrane. In mast cells, localizes to the endocytic recycling compartment.
  • Information by UniProt

画像

  • The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.

参考文献

ab91737 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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