Recombinant Human SUV420h1 protein (ab80286)

製品の概要

  • 製品名Recombinant Human SUV420h1 protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 領域2 to 387

特性

Our Abpromise guarantee covers the use of ab80286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 30% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0

関連情報

  • 別名
    • CGI 85
    • CGI85
    • Histone-lysine N-methyltransferase KMT5B
    • Kmt5b
    • KMT5B_HUMAN
    • Lysine N-methyltransferase 5B
    • Lysine-specific methyltransferase 5B
    • MGC118906
    • MGC118909
    • MGC21161
    • MGC703
    • Su(var)4-20 homolog 1
    • Suppressor of variegation 4 20 homolog 1
    • Suppressor of variegation 4-20 homolog 1
    • Suv4-20h1
    see all
  • 機能Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
  • 配列類似性Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
    Contains 1 SET domain.
  • 細胞内局在Nucleus. Chromosome. Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin (By similarity).
  • Information by UniProt

Recombinant Human SUV420h1 protein 画像

  • SDS-PAGE showing ab80286 at approximately 70kDa (3µg).

Recombinant Human SUV420h1 protein (ab80286) 使用論文

ab80286 has not yet been referenced specifically in any publications.

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