The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab117696 is purified by standard chromatography. Purity is greater than 85% as determined by SDS-PAGE.
Please prevent freeze thaw cycles.
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Shipped at 4°C. Store at -20°C. Store under desiccating conditions.
pH: 7.50 Constituents: 0.32% Tris HCl, 10% Glycerol
Hydroxysteroid sulfotransferase 2
Sulfotransferase family cytosolic 2B member 1
Catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol.
Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung.