製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected Sf9 cells
  • アミノ酸配列
    • アクセッション番号Q6J9G0
    • 生物種Human
    • 分子量67 kDa including tags
    • 領域58 to 422

関連製品

特性

Our Abpromise guarantee covers the use of ab125536 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

  • 精製度> 70 % Densitometry.
    Purity determined to be >70% by densitometry.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.29% Sodium chloride

関連情報

  • 別名
    • DKFZp761P1010
    • NOK
    • Novel oncogene with kinase domain
    • Protein kinase STYK1
    • Protein PK unique
    • Protein PK-unique
    • Serine/threonine/tyrosine kinase 1
    • Styk 1
    • STYK1
    • STYK1_HUMAN
    • SuRTK 106
    • SuRTK106
    • Tyrosine protein kinase STYK1
    • Tyrosine-protein kinase STYK1
    see all
  • 機能Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways.
  • 組織特異性Widely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells LO2, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K562, but not in other tumor cells such as epidermoid carcinoma (A431). Undetectable in most normal lung tissues, widely expressed in lung cancers.
  • 配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family.
    Contains 1 protein kinase domain.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant Human Styk1 protein 画像

  • SDS-PAGE analysis of ab125536.

Recombinant Human Styk1 protein (ab125536) 使用論文

ab125536 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"