製品の概要

法規制情報

製品の詳細

  • 由来
    Recombinant
  • 由来
    Baculovirus infected Sf9 cells
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 分子量
      63 kDa including tags
    • 領域
      1 to 545
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab107696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    Specific activity: 22 nmol/min/mg
  • アプリケーション

    SDS-PAGE

    Functional Studies

  • 精製度
    > 95 % SDS-PAGE.
    Purification determined by densitometry
  • 製品の状態
    Liquid
  • 備考

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: 150mM Imidazole
    Constituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • DCHT
    • DKFZp686K05124
    • OTTHUMP00000165175
    • PASK
    • Proline alanine rich STE20 related kinase
    • Serine threonine kinase 39
    • Serine threonine kinase 39 (STE20/SPS1 homolog yeast)
    • Serine/threonine protein kinase 39
    • Serine/threonine-protein kinase 39
    • Small intestine SPAK like kinase
    • SPAK
    • Ste 20 related kinase
    • Ste-20-related kinase
    • Ste20 like protein kinase
    • STE20/SPS1 homolog
    • STE20/SPS1 related proline alanine rich protein kinase
    • STE20/SPS1-related proline-alanine-rich protein kinase
    • STK 39
    • Stk39
    • STK39_HUMAN
    see all
  • 機能
    May act as a mediator of stress-activated signals.
  • 組織特異性
    Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis.
  • 配列類似性
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • ドメイン
    PAPA box (proline-alanine repeats) may target the kinase to a specific subcellular location by facilitating interaction with intracellular proteins such as actin or actin-like proteins.
  • 細胞内局在
    Cytoplasm. Nucleus. Nucleus when caspase-cleaved.
  • Information by UniProt

画像

  • SDS Page analysis of ab107696
  • ab107696 specific activity determined to be 22 nmol/min/mg

参考文献

ab107696 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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