製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVY MKRKYEAMTKLGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMT FGRLQGISPKIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEK IHERSGNREAQEKEERRGTAHRWSSQNTHNIGRFSLSTSMGAVHGTPKTI THNRDPKGGNMPGPTDCVRENSW
    • 分子量
      51 kDa including tags
    • 領域
      1 to 223

関連製品

特性

Our Abpromise guarantee covers the use of ab116849 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Cancer/testis antigen 5.2
    • Cancer/testis antigen family 5, member 2a
    • Cancer/testis antigen family 5, member 2b
    • CT5.2
    • CT5.2A
    • CT5.2b
    • HD21
    • hom mel 40
    • HOM-MEL-40
    • MGC119055
    • MGC15364
    • MGC3884
    • Protein SSX2
    • RP11-552J9.2
    • sarcoma, synovial, X-chromosome related 2
    • SSx
    • SSX2
    • SSX2-SYT fusion gene, included
    • SSX2_HUMAN
    • SSX2B
    • Synovial sarcoma
    • synovial sarcoma X breakpoint 2
    • Synovial sarcoma, X breakpoint 2B
    • Tumor antigen HOM-MEL-40
    • X breakpoint 2
    see all
  • 機能
    Could act as a modulator of transcription.
  • 組織特異性
    Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.
  • 関連疾患
    Note=A chromosomal aberration involving SSX2 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • 配列類似性
    Belongs to the SSX family.
    Contains 1 KRAB-related domain.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116849 at approximately 50.64 kDa.

参考文献

ab116849 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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