The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
備考Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Cancer/testis antigen 5.2
Cancer/testis antigen family 5, member 2a
Cancer/testis antigen family 5, member 2b
hom mel 40
sarcoma, synovial, X-chromosome related 2
SSX2-SYT fusion gene, included
synovial sarcoma X breakpoint 2
Synovial sarcoma, X breakpoint 2B
Tumor antigen HOM-MEL-40
X breakpoint 2
機能Could act as a modulator of transcription.
組織特異性Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.
関連疾患Note=A chromosomal aberration involving SSX2 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
配列類似性Belongs to the SSX family. Contains 1 KRAB-related domain.