製品の概要

  • 製品名
    Recombinant Human SPOP protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMSRVPSPPPPAEMSSGPVAESWCYTQIKVV KFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEES KDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKD WGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFE HEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKY ALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHAS DVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
    • 分子量
      44 kDa including tags
    • 領域
      1 to 374
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab105599 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab105599 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, 2mM EDTA, pH 8.0

関連情報

  • 別名
    • BTBD32
    • HIB homolog 1
    • Roadkill homolog 1
    • Speckle type POZ protein
    • Speckle-type POZ protein
    • SPOP
    • SPOP_HUMAN
    • TEF 2
    • TEF2
    see all
  • 機能
    Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.
  • 組織特異性
    Widely expressed.
  • パスウェイ
    Protein modification; protein ubiquitination.
  • 配列類似性
    Belongs to the Tdpoz family.
    Contains 1 BTB (POZ) domain.
    Contains 1 MATH domain.
  • ドメイン
    The MATH domain interacts with H2AFY and BMI1.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

Recombinant Human SPOP protein 画像

  • 15% SDS-PAGE analysis of 3µg ab105599.

Recombinant Human SPOP protein (ab105599) 使用論文

ab105599 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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