製品の概要

  • 製品名Recombinant Human SP110 protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号Q9HB58
    • 生物種Human
    • 配列TPSDKKGKKRKRCIWSTPKRRHKKKSLPRGTASSRHGIQKKLKRVDQVPQ KKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPST PRRVTQGAAS
    • 分子量38 kDa including tags
    • 領域271 to 380

関連製品

特性

Our Abpromise guarantee covers the use of ab114669 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • FLJ22835
    • IFI 41
    • IFI 75
    • IFI41
    • IFI75
    • Interferon induced protein 41
    • Interferon induced protein 41 30kD
    • Interferon induced protein 41/75
    • Interferon induced protein 75
    • Interferon induced protein 75 52kD
    • Interferon-induced protein 41/75
    • IPR 1
    • IPR1
    • Phosphoprotein 41
    • Phosphoprotein 75
    • SP 110
    • SP110
    • Sp110 nuclear body protein
    • SP110_HUMAN
    • Speckled 110 kDa
    • Transcriptional coactivator Sp110
    • VODI
    see all
  • 機能Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE).
  • 組織特異性Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 関連疾患Defects in SP110 are the cause of hepatic venoocclusive disease with immunodeficiency (VODI) [MIM:235550]. VODI is an autosomal recessive primary immunodeficiency associated with hepatic vascular occlusion and fibrosis. The immunodeficiency is characterized by severe hypogammaglobulinemia, combined T and B cell immunodeficiency, absent lymph node germinal centers, and absent tissue plasma cells.
  • 配列類似性Contains 1 bromo domain.
    Contains 1 HSR domain.
    Contains 1 PHD-type zinc finger.
    Contains 1 SAND domain.
  • 翻訳後修飾Phosphorylated (isoform 2).
  • 細胞内局在Nucleus. Found in the nuclear body.
  • Information by UniProt

Recombinant Human SP110 protein 画像

  • SDS-PAGE analysis of ab114669 on a 12.5% gel stained with Coomassie Blue.

Recombinant Human SP110 protein (ab114669) 使用論文

ab114669 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114669.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"