Recombinant Human SOD2/MnSOD protein (ab82656)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab82656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Western blot

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20mM HEPES, pH 7

  • 再構成Reconstitute in 500µl of DW

関連情報

  • 別名
    • Indophenoloxidase B
    • IPO B
    • IPOB
    • Manganese containing superoxide dismutase
    • Manganese SOD
    • Manganese superoxide dismutase
    • Mangano superoxide dismutase
    • Mn SOD
    • Mn superoxide dismutase
    • MNSOD
    • MVCD6
    • SOD 2
    • SOD2
    • SODM_HUMAN
    • Superoxide dismutase [Mn] mitochondrial
    • Superoxide dismutase [Mn], mitochondrial
    • Superoxide dismutase 2 mitochondrial
    see all
  • 機能Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
  • 関連疾患Genetic variation in SOD2 is associated with susceptibility to microvascular complications of diabetes type 6 (MVCD6) [MIM:612634]. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.
  • 配列類似性Belongs to the iron/manganese superoxide dismutase family.
  • 翻訳後修飾Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity.
  • 細胞内局在Mitochondrion matrix.
  • Information by UniProt

Recombinant Human SOD2/MnSOD protein 画像

  • ab82656 at 1µg on SDS-PAGE.

  • Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 12 minutes

Recombinant Human SOD2/MnSOD protein (ab82656) 使用論文

ab82656 has not yet been referenced specifically in any publications.

Product Wall

This protein is the full length SOD2 protein without the transit peptide which corresponds to amino acids 1-24.

Therefore the protein consists of amino acids 25-222 of the human protein: http://www.uniprot.org/uniprot/P04179

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"