製品の概要

法規制情報

製品の詳細

  • 由来
    Recombinant
  • 由来
    Baculovirus infected Sf9 cells
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 分子量
      71 kDa including tags
    • 領域
      1 to 428
    • タグ
      GST tag N-Terminus

関連製品

特性

Our Abpromise guarantee covers the use of ab125590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 0.25% Glycerol, 0.88% Sodium chloride

関連情報

  • 別名
    • bA74P14.1
    • bA74P14.1 (novel protein)
    • FLJ21080
    • histone lysine N methyltransferase SMYD3
    • KMT3E
    • MGC104324
    • SET and MYND domain containing 3
    • SET and MYND domain containing protein 3
    • SET and MYND domain-containing protein 3
    • SMYD 3
    • Smyd3
    • SMYD3 protein
    • SMYD3_HUMAN
    • Zinc finger MYND domain containing 1
    • Zinc finger MYND domain containing protein 1
    • Zinc finger MYND domain-containing protein 1
    • Zinc finger protein subfamily 3A MYND domain containing 1
    • Zinc finger protein, subfamily 3A (MYND domain containing), 1
    • ZMYND 1
    • ZMYND1
    • ZNFN3A1
    see all
  • 機能
    Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.
  • 組織特異性
    Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas.
  • 配列類似性
    Belongs to the histone-lysine methyltransferase family.
    Contains 1 MYND-type zinc finger.
    Contains 1 SET domain.
  • 細胞内局在
    Cytoplasm. Nucleus. Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M.
  • Information by UniProt

画像

  • SDS page analysis of ab125590

参考文献

ab125590 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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